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Edda Spiekerkoetter 1The Vera Moulton Wall Center for Pulmonary Vascular Disease, 2Department of Medicine, and 3Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA. 4Department of Molecular Cell Biology, Cancer Genomics Center and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, Netherlands. 5Department of Pediatrics, 6High-Throughput Bioscience Center, 7Department of Biochemistry, and 8Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California, USA. Xuefei Tian 1The Vera Moulton Wall Center for Pulmonary Vascular Disease, 2Department of Medicine, and 3Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA. 4Department of Molecular Cell Biology, Cancer Genomics Center and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, Netherlands. 5Department of Pediatrics, 6High-Throughput Bioscience Center, 7Department of Biochemistry, and 8Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California, USA. Jie Cai 1The Vera Moulton Wall Center for Pulmonary Vascular Disease, 2Department of Medicine, and 3Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA.

4Department of Molecular Cell Biology, Cancer Genomics Center and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, Netherlands. 5Department of Pediatrics, 6High-Throughput Bioscience Center, 7Department of Biochemistry, and 8Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California, USA. Hopper 1The Vera Moulton Wall Center for Pulmonary Vascular Disease, 2Department of Medicine, and 3Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA. 4Department of Molecular Cell Biology, Cancer Genomics Center and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, Netherlands. 5Department of Pediatrics, 6High-Throughput Bioscience Center, 7Department of Biochemistry, and 8Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California, USA. Deepti Sudheendra 1The Vera Moulton Wall Center for Pulmonary Vascular Disease, 2Department of Medicine, and 3Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA.

4Department of Molecular Cell Biology, Cancer Genomics Center and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, Netherlands. 5Department of Pediatrics, 6High-Throughput Bioscience Center, 7Department of Biochemistry, and 8Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California, USA. Li 1The Vera Moulton Wall Center for Pulmonary Vascular Disease, 2Department of Medicine, and 3Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA. 4Department of Molecular Cell Biology, Cancer Genomics Center and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, Netherlands.

5Department of Pediatrics, 6High-Throughput Bioscience Center, 7Department of Biochemistry, and 8Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California, USA. Nesrine El-Bizri 1The Vera Moulton Wall Center for Pulmonary Vascular Disease, 2Department of Medicine, and 3Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA. 4Department of Molecular Cell Biology, Cancer Genomics Center and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, Netherlands. 5Department of Pediatrics, 6High-Throughput Bioscience Center, 7Department of Biochemistry, and 8Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California, USA. Hirofumi Sawada 1The Vera Moulton Wall Center for Pulmonary Vascular Disease, 2Department of Medicine, and 3Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA. 4Department of Molecular Cell Biology, Cancer Genomics Center and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, Netherlands. 5Department of Pediatrics, 6High-Throughput Bioscience Center, 7Department of Biochemistry, and 8Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California, USA.